Players scrub up and prepare for virtual surgery in the Operating Room simulation brought Stateside by Atlus. The main gameplay in Trauma Center is akin to a high-tech version of the 1960s board game Operation; players use their DS stylus to apply anesthetic to, make incisions in, and remove failing body parts from their touch-screen patients. In light role-playing segments, away from the O.R., players will also need to demonstrate a decent bedside manner, to help their patients to keep a positive, curative attitude.