Players of all ages once again join "those meddling kids," to solve a movie masquerade mystery in Scooby-Doo! Unmasked. The kids have gone to visit Freddy's cousin, Jed, but find that he's disappeared from the monster movie set where he was working. To find Jed (and to clear his name of the crime he is said to have committed), players must guide Scooby through three different areas, in the spooky movie studio and beyond, looking for clues. By donning different movie costumes, Scooby can gain new abilities that might help him get past obstacles and bad guys. The voices of Scooby, Shaggy, and rest of the gang are performed by actors who portrayed them in the various cartoon series, and the game's main villain, Winslow Stanton, is played by Adam West (Batman, Family Guy).