Agatha Christie: The ABC Murders once again finds gamers helping the balding Belgian detective Hercule Poirot, this time in an effort to track down a serial killer who has been dispatching his victims in alphabetical order. The killer taunts Poirot by revealing the location of each murder beforehand and leaving an ABC Railway Guide with each body, but the detective always arrives too late. It's up to players to enlist the help of Hastings and Japp, use the touch screen to inspect crime scenes, interact with 20 different characters and suspects, and travel throughout England on the hunt for the ABC killer.