Based on the true story of a research physician who uses an experimental drug to "awaken" the catatonic victims of a rare sleeping sickness. The first patient to receive the drug (De Niro in an astounding performance) is filled with awe and enthusiasm that teaches the introverted doctor to value life's simple pleasures. Academy Award Nominations: 3, including Best Picture, Best Actor--Robert De Niro, Best (Adapted) Screenplay.