Frontline is a flea and tick product that provides up to 30 days of protection with one dose. This Frontline product is designed for extra large dogs that weigh between 89 and 132 pounds. Each dose comes in a vial that you clip and then pour on between the dog's shoulder blades. The active ingredient in the product is fipronil. This medication is intended for dogs eight weeks of age and older as well as those who are not pregnant or nursing.